Product Name :
3,5-Dimethylaniline (CAS 108-69-0)
Synonym :
1-Amino-3,5-dimethylbenzene; 3,5-Xylidine; 5-Amino-m-xylene
Application :
CAS:
108-69-0
Purity:
Molecular Weight:
121.18
Formula :
C8H11N
Physical state:
Liquid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
7-9° C
SMILES:
CC1=CC(=CC(=C1)N)C
References:
:2,4-disubstituted pyrimidines: a novel class of KDR kinase inhibitors.1600425-77-1 MDL No. | Manley, PJ.32477-35-3 site , et al.PMID:33397183 2003. Bioorg Med Chem Lett. 13: 1673-7. PMID: 12729639Identification of adducts formed by reaction of N-acetoxy-3,5-dimethylaniline with DNA. | Cui, L., et al. 2007. Chem Res Toxicol. 20: 1730-6. PMID: 18020398Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography–electrospray ionization tandem mass spectrometry. | Strife, RJ., et al. 2009. J Chromatogr A. 1216: 6970-3. PMID: 19733358Genotoxicity of 2,6- and 3,5-dimethylaniline in cultured mammalian cells: the role of reactive oxygen species. | Chao, MW., et al. 2012. Toxicol Sci. 130: 48-59. PMID: 22831970Intracellular generation of ROS by 3,5-dimethylaminophenol: persistence, cellular response, and impact of molecular toxicity. | Chao, MW., et al. 2014. Toxicol Sci. 141: 300-13. PMID: 24973092Cytoplasmic and nuclear toxicity of 3,5-dimethylaminophenol and potential protection by selenocompounds. | Erkekoglu, P., et al. 2014. Food Chem Toxicol. 72: 98-110. PMID: 25014158Protective effects of ascorbic acid against the genetic and epigenetic alterations induced by 3,5-dimethylaminophenol in AA8 cells. | Chao, MW., et al. 2015. J Appl Toxicol. 35: 466-77. PMID: 25178734Ultraviolet relaxation dynamics of aniline, N, N-dimethylaniline and 3,5-dimethylaniline at 250 nm. | Thompson, JO., et al. 2015. J Chem Phys. 142: 114309. PMID: 25796251Anti-cancer effects of 3,5-dimethylaminophenol in A549 lung cancer cells. | Lin, PY., et al. 2018. PLoS One. 13: e0205249. PMID: 30307971In Vitro and In Vivo Analysis of the Effects of 3,5-DMA and Its Metabolites in Neural Oxidative Stress and Neurodevelopmental Toxicity. | Chao, MW., et al. 2019. Toxicol Sci. 168: 405-419. PMID: 30590852Antioxidants and selenocompounds inhibit 3,5-dimethylaminophenol toxicity to human urothelial cells. | Erkekoglu, P., et al. 2019. Arh Hig Rada Toksikol. 70: 18-29. PMID: 30956221Synthesis of alpha , delta -Disubstituted Tetraphosphates and Terminally-Functionalized Nucleoside Pentaphosphates. | Shepard, SM., et al. 2021. J Am Chem Soc. 143: 463-470. PMID: 33375782Differences in Pharmacokinetics and Haematotoxicities of Aniline and Its Dimethyl Derivatives Orally Administered in Rats. | Miura, T., et al. 2021. Biol Pharm Bull. 44: 1775-1780. PMID: 34433705