Product Name :
VAMP2 Recombinant Rabbit Monoclonal Antibody [JM11-00]
Predicted band size :
Observed band size :
Synonyms:
FLJ11460 antibody RATVAMPB antibody RATVAMPIR antibody SYB antibody SYB2 antibody Synaptobrevin 2 antibody Synaptobrevin-2 antibody VAMP 2 antibody VAMP-2 antibody Vamp2 antibody 展开
Function :
Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25 kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including a- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human VAMP2 aa 9-42 / 116.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, FC, IP, IHC-P
Coupling :
unconjugated
Clone number:
JM11-00
RRID:
AB_3070406
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2413767-30-1 Chemscene Aliquot store at -20℃ or -80℃.1015610-39-5 site Avoid repeated freeze / thaw cycles.PMID:33645442
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 13 kDa
Positive control :
Jurkat cell lysates, N2A, SH-SY5Y, SHG-44, mouse brain tissue, rat brain tissue.