Product Name :
SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75]
Predicted band size :
Observed band size :
Synonyms:
BAM antibody Bamacan antibody Basement membrane associated chondroitin proteoglycan antibody Basement membrane-associated chondroitin proteoglycan antibody BMH antibody CDLS3 antibody chondroitin sulfate proteoglycan 6 (bamacan) antibody Chondroitin sulfate proteoglycan 6 antibody Chromosome associated polypeptide antibody Chromosome-associated polypeptide antibody 展开
Function :
The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein and Bamacan for the secreted proteoglycan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis, and colon.1-(2-N-Boc-aminoethyl)piperazine Formula SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan expressed in testis and brain. The secreted proteoglycan contains several glycosylation sites and is thought to play a role in basement membrane physiology.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human SMC3 aa 1994-1217 / 1217.Price of 25055-86-1
Species reactivity:
Human, Mouse, Rat, Zebrafish
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JM10-75
RRID:
AB_3070392
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.PMID:33380273
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 142 kDa
Positive control :
HepG2 cell lysate, NIH-3T3 cell lysate, PC12 cell lysate, Hela, HepG2, NIH-3T3, human tonsil tissue, human colon cancer tissue, human kidney tissue, mouse colon tissue, zebrafish tissue.