Product Name :
RPE65 Recombinant Rabbit Monoclonal Antibody [JM61-51]
Predicted band size :
Observed band size :
Synonyms:
All-trans-retinyl-palmitate hydrolase antibody LCA 2 antibody LCA2 antibody Leber congenital amaurosis antibody mRPE 65 antibody mRPE65 antibody p63 antibody rd 12 antibody rd12 antibody Retinal pigment epithelium specific 61 kDa protein antibody 展开
Function :
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65kDa protein belonging to the beta-carotene dioxygenase family.69812-51-7 site This protein is important in 11-cis retinal production as well as in visual pigment regeneration.Buy1,3,5-Trivinylbenzene RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A.PMID:33472544 Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human RPE65 aa 441-484 / 533.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IHC-P
Coupling :
unconjugated
Clone number:
JM61-51
RRID:
AB_3070437
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 61 kDa
Positive control :
Mouse eyeball tissue lysates, rat eyeball tissue, mouse eyeball tissue.